Figure 1, The steps of regenerative medicine. - StemBook - NCBI
By A Mystery Man Writer
Description
The production of cellular therapies requires the optimization of four steps: first, isolating and culturing cells that can be readily obtained from a patient in a non-invasive fashion. Second, the reprogramming of these cells into a pluripotent state. Third, the directed differentiation of those patient-specific pluripotent cells into the cell type relevant to their disease. And, fourth, techniques for repairing any intrinsic disease-causing genetic defects and transplantation of the repaired, differentiated cells into the patient. Notably, these disease-relevant patient cells can also be used for in vitro disease modeling which may yield new insights into disease mechanisms and drug discovery.
Identification of hurdles in the development of cell-based
Figure 2, Example genome editing target site showing TALEN design
Hematopoietic differentiation - StemBook - NCBI Bookshelf
Frontiers Regenerative medicine technologies applied to
Hematopoietic differentiation - StemBook - NCBI Bookshelf
Stem cells: past, present, and future
Frontiers Using Advanced Cell Culture Techniques to
Differential role of natural killer group 2D in recognition and
Figure 8, An example of hepatoblast delamination. - StemBook
Frontiers Dental Pulp Stem Cells Derived From Adult Human Third
Cell differentiation - Definition and Examples - Biology Online
Developments in cell culture systems for human pluripotent stem cells
A roundtable on responsible innovation with autologous stem cells
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