A protein with a dual role: Both repair and mutation
By A Mystery Man Writer
Description
Using a specialized protein, all bacteria are capable of rapidly and effectively repairing damage to their DNA from UV. However, this mutation frequency decline (Mfd) protein plays another role and causes mutations. A team1 involving scientists from CNRS, ENS-PSL and supported by Inserm has demonstrated and described this phenomenon. Better understanding of mutations opens up prospects in the fight against resistance to antibiotics and anti-cancer therapies. This study was published in PNAS on 5 April 2021.
Microtubule-associated proteins MAP7 and MAP7D1 promote DNA double-strand break repair in the G1 cell cycle phase - ScienceDirect
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Protein and Scientist - Clinical Research Informer
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Double-strand break repair model - Wikipedia
A protein with a dual role: Both repair and mutation
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DNA Repair Protein - an overview
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